A new derivative of vitamin C and its application to the synthesis of labelled ascorbic acid
- 1 March 1966
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 98 (3) , 652-654
- https://doi.org/10.1042/bj0980652
Abstract
The preparation of a mono-0-cyclohexylidene derivative of L-ascorbic acid is described. The new compound is shielded by the cyclohexanone group at C-5 and C-6 of the ascorbic acid molecule, while the double bond between C-2 and C-3 is kept intact. The double bond of the new derivative is more resistant to oxidation than its parent compound. Ascorbic acid is easily regenerated by mild acid hydrolysis. The new derivative facilitates the synthesis of C14-labeled vitamin C.This publication has 2 references indexed in Scilit:
- Separation of Substances Related to Ascorbic AcidNature, 1949
- Filter-paper partition chromatography of sugarsBiochemical Journal, 1947