URINARY PREGN-5-ENE-3α, 16α,20α-TRIOL IN ADRENAL DYSFUNCTION

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Abstract
SUMMARY Pregn-5-ene-3α, 16α,20α-triol in amounts from 50 to 220 μg/24 h was found in the urine of normal adult men and women. Excretion within this range was also found in five adult women of whom two had congenital adrenal hyperplasia, one had Cushing's disease, one was hirsute and infertile and one was obese. Except for one patient, who excreted amounts within the normal range, subjects with adrenal carcinoma excreted up to 15 mg of this steroid/24 h.

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