Fragile X trait in a large kindred: transmission also through normal males.
Open Access
- 1 August 1983
- journal article
- Published by BMJ in Journal of Medical Genetics
- Vol. 20 (4) , 286-289
- https://doi.org/10.1136/jmg.20.4.286
Abstract
In the pedigree reported here two apparently normal males may have transmitted the fragile X chromosome. Eighteen family members were examined cytogenetically. The fragile X was detected in a high percentage of cells from nine mentally retarded members of this family (six males and three females) and in one female obligate carrier. Four other obligate carriers showed no or only a few cells with the fragile X.Keywords
This publication has 11 references indexed in Scilit:
- Transmission of fragile (X)(q27) from normal male(s)Human Genetics, 1982
- Marker X syndrome in an oriental family with probable transmission by a normal maleAmerican Journal of Medical Genetics, 1982
- FRAGILE X‐LINKED MENTAL RETARDATION: THE MARTIN‐BELL SYNDROMEJournal of Intellectual Disability Research, 1981
- TRANSMISSION OF FRAGILE (X) (q27) SITE FROM A MALEThe Lancet, 1981
- X-Linked mental retardation with fragile X. a pedigree showing transmission by apparently unaffected males and partial expression in female carriersHuman Genetics, 1981
- FRAGILE X IN A NORMAL MALE: A CAUTIONARY TALEThe Lancet, 1981
- Familial X‐linked mental retardation and fragile X chromosomes in two Swedish familiesClinical Genetics, 1981
- X-linked mental retardation, macro-orchidism, and the Xq27 fragile siteThe Journal of Pediatrics, 1980
- X‐linked mental retardation: A study of 7 familiesAmerican Journal of Medical Genetics, 1980
- Heritable fragile sites on human chromosomesHuman Genetics, 1979