Affinity chromatography used in distinguishing alpha-fetoprotein in serum from patients with tumors of hepatic parenchyma and of germ cells.
- 1 July 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 30 (7) , 1257-1258
- https://doi.org/10.1093/clinchem/30.7.1257
Abstract
We used affinity chromatography on concanavalin A Sepharose to study the serum alpha-fetoprotein of 10 patients with histologically proven germ-cell tumors and 12 patients with primary liver cancer. Less than 50% of the fetoprotein from germ-cell tumors bound to concanavalin A, as compared with more than 80% of the alpha-fetoprotein from primary liver cancers.Keywords
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