Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in Vivo
Open Access
- 1 December 2000
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 275 (50) , 38990-38994
- https://doi.org/10.1074/jbc.m006490200
Abstract
No abstract availableKeywords
This publication has 20 references indexed in Scilit:
- Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless MiceJournal of Biological Chemistry, 2000
- Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2Journal of Clinical Investigation, 2000
- Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signallingNature Genetics, 1999
- The 60-kDa Phosphotyrosine Protein in Insulin-treated Adipocytes Is a New Member of the Insulin Receptor Substrate FamilyJournal of Biological Chemistry, 1997
- Insulin Signalling and Insulin Actions in the Muscles and Livers of Insulin-Resistant, Insulin Receptor Substrate 1-Deficient MiceMolecular and Cellular Biology, 1996
- Role of IRS-2 in insulin and cytokine signallingNature, 1995
- Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 geneNature, 1994
- Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1Nature, 1994
- What if Minkowski Had Been Ageusic? An Alternative Angle on DiabetesScience, 1992
- Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction proteinNature, 1991