Fungal products. Part VIII. New kaurenolides from Gibberella fujikuroi

1 January 1973

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1

p. 2773-2778
https://doi.org/10.1039/p19730002773

Abstract

The isolation of four new kaurenolides from the culture filtrates of Gibberella fujikuroi strain TP70 is described. Structures (4), (6), (9), and (10), deduced for these metabolites from chemical and spectroscopic data, represent three new positions (at C-1, -3, and -11) of hydroxylation of ent-kaur-16-ene by this fungus. In addition 7β,11α-dihydroxy-18-norkaurenolide (11) has been isolated.

Keywords

STRUCTURES
VIII
NEW KAURENOLIDES
FUJIKUROI
GIBBERELLA
11Α
METABOLITES
SPECTROSCOPIC