Sprechstundenblutdruck, Heimblutdruck, Ergometer-Blutdruck und 24-Stunden-Blutdruck: Korrelationen mit echokardiographischen Parametern der Herzmuskelmasse

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Abstract
In 62 untreated hypertensives (31 men, 31 women; median age 40 [17-57] years) blood pressures (BP) were measured in the doctor''s office, at home (self-measured) and every 15 min during 24-hour monitoring (by portable automated oscillometry), the results being compared with echocardiographic measurements of ventricular septal thickness (VST), left ventricular muscle mass (LVM) and left ventricular mass index (LVMI), in 41 of them also during and 5 min after 100 W bicycle ergometry. In the total cohort, 24-hour values correlated better with diastolic VST (systolic: r = 0.706, P < 0.00001; diastolic: r = 0.507, P < 0.0001) than office BP (systolic: r = 0.381, P < 0.01; diastolic r = 0.177, not significant) and home BP (systolic: r = 0.477, P < 0.0001; diastolic: r = 0.371, P < 0.05). In the 41 exercised hypertensives the correlation with echocardiographic values was less close than with their 24-hour BP, but slightly better than with office and home BP. Systolic BP correlated better than diastolic BP with echocardiographic values. VST generally correlated better with BP than LVM and LVMI. It is concluded that (1) 24-hour BP values correlate more closely with LVM than any other noninvasive BP measurement; (2) VST is affected more by systolic than diastolic BP; and (3) VST more specifically reflects the influence of BP on myocardial structure than does LVM and LVMI.