Prediction of Spleen Size by Routine Radioisotope Scintigraphy

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Abstract
99mTc scintigraphy of the spleen was performed in 32 patients with various hematologic disorders prior to splenectomy. From the .gamma.-camera image of the spleen, the weight of the spleen was estimated using 2 different mathematical formulas and the results obtained were compared to the postoperative spleen weight. Both formulas revealed spleen weights showing highly significant correlations to the postoperative spleen weight and with similar standard deviations. Visual evaluation of the scintigram by an experienced examiner with classification of the spleens into 4 groups according to spleen weight revealed results as good as the mathematical calculations in predicting the postoperative spleen weight, both techniques giving diagnostic specificities of 0.70-0.80 for all groups and diagnostic sensitivities of 0.80-1.00. Physical examination of the abdomen showed that .apprx. 50% of the spleens weighing from 250-1000 g were not palpable. Physical examination of the abdomen alone apparently is unreliable. Radioisotope scintigraphy of the spleen is recommended, this method being fast, with negligible discomfort to the patient and with sufficient accuracy for daily clinical work.

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