Blood screening by nucleic acid amplification technology: current issues, future challenges.
- 1 March 2000
- journal article
- Vol. 5 (1)
- https://doi.org/10.1054/MODI00500011
Abstract
Nucleic acid amplification technology (NAT) is presently being evaluated in US clinical trials to determine the safety and efficacy of mini-pool testing for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) RNA in the blood-donor population. Although the risk for transfusion-transmitted HIV and HCV infection is extremely low, there is still a small chance that blood donated by infected individuals before seroconversion can escape detection by current antibody-based assays.Keywords
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