Protein and Platelet Interactions with Polymer Surfaces
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Biomaterials, Medical Devices, and Artificial Organs
- Vol. 12 (3-4) , 235-266
- https://doi.org/10.3109/10731198409118834
Abstract
An attempt is made to develop an understanding of the basic mechanism governing the interaction of the major blood proteins and cells with polymer surfaces with a focus on thermodynamic approach. It is believed that such investigations may be helpful to provide a rational for the design of suitable cardiovascular prosthetic materials and to choose materials in such a way that adsorption of certain proteins eg. ‘fibrinogen’ is thermodynamically unfavourable compared to adsorption of other proteins eg. ‘albumin’.Keywords
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