Effects of gamma‐hydroxybutyrate on chick behaviour, electrocortical activity and crossed extensor reflexes
Open Access
- 1 April 1972
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 44 (4) , 593-604
- https://doi.org/10.1111/j.1476-5381.1972.tb07299.x
Abstract
1 Convulsant and anticonvulsant effects of gamma-hydroxybutyrate (GHB) have been studied in chicks. 2 When administered alone, GHB produced weak myoclonic seizures accompanied by electrocortical synchrony and spikes. 3 GHB was found to protect chicks against leptazol- and picrotoxin-induced seizures. A slight potentiation of strychnine-induced seizures was evident.Keywords
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