NEONATAL PANCREATIC BETA-CELL HYPERPLASIA - REPORT OF A CASE WITH FAILURE OF DIAZOXIDE AND BENEFIT OF EARLY SUBTOTAL PANCREATECTOMY

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 57  (6) , 897-900
Abstract
A newborn infant with pancreatic .beta.-cell hyperplasia had persistent hypoglycemia due to hyperinsulinism. After medical management, including the use of diazoxide and constant glucose infusions had proved ineffective, a subtotal pancreatectomy was curative. Cumulative experience seems to indicate that there should be little delay in performing a subtotal pancreatectomy when aggressive medical management cannot maintain normoglycemia in a neonate.