ATYPICAL MIXED LYMPHOCYTE CULTURE IDENTITY BETWEEN MOTHER AND CHILD IN LEUKEMIA AND APLASTIC ANEMIA

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Abstract
The mixed lymphocyte culture tests between one patient with acute lymphocytic leukemia and her mother and between another patient with aplastic anemia and his mother were found nonreactive, despite a one-haplotype difference for HL-A. Two crossovers in each family at the MLC locus or a specific defect in lymphocyte responsiveness could be possibly explantations. The mother of each patient could be considered a potential donor for bone marrow transplantation.

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