12pter ? 12p 12.2: Possible assignment of human triose phosphate isomerase
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 36 (2) , 235-237
- https://doi.org/10.1007/bf00273263
Abstract
Red cell triose-phosphate isomerase (TPI) was determined, together with other enzymes, in three patients with chromosome 12 abnormalities. In patient No. 1 (trisomy of the segment 12pter → 12q12) and in patient No. 2 (trisomy of the segment 12pter → 12p12.1), the TPI activity was significantly increased. In patient No. 3 (deletion of the segment 12p11 → 12p12.2), the TPI activity was in the normal range. These results suggest that the human TPI locus is located on the chromosome 12 short arm, between 12pter and 12p12.2.Keywords
This publication has 5 references indexed in Scilit:
- LOCALIZATION OF GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (G3PD) LOCUS ON DISTAL PART OF 12P1976
- Gene dosage effect in human triploid fibroblastsHuman Genetics, 1976
- [Increase of the LDH-B activity in a boy with 12p trisomy by malsegregation of a maternal translocation t(12;14) (q12;p11)].1975
- Evidence for Synteny between the Human Loci for Triose Phosphate Isomerase, Lactate Dehydrogenase-B, and Peptidase-B and the Regional Mapping of these Loci on Chromosome 12Cytogenetic and Genome Research, 1974
- [A new technic of analysis of the human karyotype].1971