The effect of tunicamycin on cell-surface changes associated with development and differentiation of Dictyostelium discoideum

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Abstract
Developmental changes in surface properties of Dictyostelium discoideum cells have been detected by partitioning. Changes occurring between 0 and 6 h development were not affected by tunicamycin but subsequent changes associated with formation of presumptive spore cells were inhibited. It would seem that only the latter changes are dependent on glyco-protein synthesis.