Studies of Antibodies to 1956 and 1963 Equine Influenza Viruses in Horses and Man
Open Access
- 1 April 1965
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 94 (4) , 563-566
- https://doi.org/10.4049/jimmunol.94.4.563
Abstract
Summary: Fourteen of 30 horses with pre-existing hemagglutination inhibition (HI) antibodies to A/Equine-1/Prague/1/56 virus exhibited 4-fold or greater rise in titer after infection with the A/Equine-2/63 agent. These findings give further evidence of shared viral antigens among the two families of Type A/Equine virus. HI and neutralizing antibodies to A/Equine-2/63 virus were found in human serum from individuals born between 1870 and 1900. Persons born about 1880 to 1890, however, exhibited higher levels and higher frequencies of antibody than did younger or older individuals. The results suggest a relationship between hemagglutination (HA) antigens of the 1963 equine strains and a virus formerly prevalent in man.Keywords
This publication has 1 reference indexed in Scilit:
- THE CLINICAL EPIDEMIOLOGY OF ASIAN INFLUENZAAnnals of Internal Medicine, 1958