Relation Between Plasma Iron Turnover and Plasma Iron Concentration at Different Levels of Erythropoiesis

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Abstract
1) The relation between plasma iron turnover and plasma iron concentration is studied in normal and fasted rabbits, in bled and phenylhydrazine treated rabbits, and in rabbits treated with extracts of plasma of bled and phenylhydrazine-treated donors. 2) In normal, phenylhydrazine-treated and starved rabbits, plasma iron turnover is independent of iron concentration over the range of 2-5 μg Fe/ml; below this range plasma iron turnover in normal rabbits tends to drop. Bled rabbits and rabbits receiving extracts with erythropoietic activity show lower plasma iron concentrations than normal, and in these animals plasma iron turnover depends on iron concentration.