Chemiluminescence response of human blood mononuclear cells to PHA and histamine
- 1 March 1983
- journal article
- histamine and-immunology
- Published by Springer Nature in Inflammation Research
- Vol. 13 (2-3) , 237-240
- https://doi.org/10.1007/bf01967341
Abstract
Phytohaemagglutinin (PHA) elicited a short early chemiluminescence (CL) response of human blood mononuclear cells with a maximum at 2.5 min. The magnitude of the CL production was a function of the PHA concentration used. The CL response could be dose-dependently inhibited by histamine. In the presence of mepyramine the action of histamine was more pronounced while a dose-dependent reversal of the inhibition was found by cimetidine.Keywords
This publication has 10 references indexed in Scilit:
- Cellular interactions in the generation and expression of histamine-induced suppressor activityCellular Immunology, 1982
- Histamine modulates in vitro IgG production by pokeweed mitogen-stimulated human mononuclear cellsCellular Immunology, 1981
- Effect of histamine on the mitogenic response of human lymphocytes and its modification by cimetidine and levamisoleInflammation Research, 1981
- The regulatory effect of histamine on the immune response: Characterization of the cells involvedCellular Immunology, 1980
- Sendai virus stimulates chemiluminescence in mouse T and B lymphocytesEuropean Journal of Immunology, 1980
- Chemiluminescence and Immune Cell Activation: General Features of the Thymocyte Chemiluminescent Responses to Plant LectinsImmunological Communications, 1980
- Chemiluminescence and immune cell activation II. Enhancement of concanavalin A‐induced chemiluminescence following in vitro preincubation of rat thymocytes; dependency on macrophage‐ lymphocyte interactionEuropean Journal of Immunology, 1980
- Chemiluminescence and immune cell activation I. Early activation of rat thymocytes can be monitored by chemiluminescence measurementsEuropean Journal of Immunology, 1978
- Histamine Inhibition of Neutrophil Lysosomal Enzyme Release: an H2 Histamine Receptor ResponseScience, 1976
- Phagocytic activation of a luminol-dependent chemiluminescence in rabbit alveolar and peritoneal macrophagesBiochemical and Biophysical Research Communications, 1976