A New Frontier for Infectious Disease Research?
- 5 August 1976
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 295 (6) , 337
- https://doi.org/10.1056/nejm197608052950610
Abstract
The malarial parasite must enter the erythrocyte of its host before it is able to undergo multiplication. In the absence of this replicative step, malarial infection would be a trivial, self-limited condition. Invasion of the erythrocyte is obviously a key step in this process and presumably involves more than mere mechanical penetration, since the membrane is intact afterward. In keeping with these notions, Miller and his co-workers have now shown that infection of the red cell by several species of malaria is apparently dependent upon a specific membrane factor either dictated by or genetically associated with the Duffy blood group. . . .Keywords
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