Acute Immune Intravascular Hemolysis due to Hydrochlorothiazide
Open Access
- 1 July 1981
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 76 (1) , 73-78
- https://doi.org/10.1093/ajcp/76.1.73
Abstract
Acute near-fatal intravascular hemolysis and renal failure developed in a patient after he had ingested IS to 20 tablets of both methyldopa (Aldomet®) and hydrochlorothiazide (HydroDiuril®). Serologic test results were inconsistent with those associated with methyldopa-induced hemolytic anemia and suggested that hemolysis was caused by hydrochlorothiazide antibodies reacting by an immune complex mechanism.Keywords
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