Absence of the pituitary gland in a case of congenital sacral agenesis

Abstract
We report for the first time the combination of congenital sacral agenesis and congenital absence of the pituitary gland. This rare association is described in a baby born to a diabetic mother. The baby died at the age of 11 weeks after a cardiorespiratory collapse. The findings at necropsy, which included unusual neurological and visceral anomalies, are reported. We draw attention to the increasing evidence that maternal diabetes is a factor in producing foetal malformations.

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