Treatment of Chronic Lymphocytic Leukemia by Extracorporeal Irradiation

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Abstract
Six patients with advanced chronic lymphocytic leukemia were treated with extracorporeal irradiation and followed for one to three years. There was a marked reduction in the circulating white cells in all patients, but in four cases the white cell counts returned to high levels in 3-7 months. Two patients are in good partial remission 37 and 22 months after the initial course of ECI. Clinical and hematological events in these cases are detailed. It was concluded that ECI is effective in lowering leukocyte levels without systemic toxicity and is beneficial in some cases of chronic lymphocytic leukemia.