Retrospective Analysis of Treatment of Acute Myeloblastic Leukemia in Patients More Than 55 Years Old

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Abstract
150 patients with acute myeloblastic leukemia were admitted from 1971 to 1980; 59 were more than 55 years old. For remission induction, three polychemotherapeutic schedules including different doses of anthracyclines were used. Complete remission was obtained in about 50% of patients less than 55 years, whereas in the elderly people complete remission rate ranged from 12 to 32%. The median duration of complete remission was, in this latter group of patients, 3 months and did not appear to be related to the aggressive regimen employed during the induction phase.