Major histocompatibility complex class II polymorphisms in humans and chimpanzees
- 1 January 1993
- journal article
- research article
- Published by Wiley in Journal of Medical Primatology
- Vol. 22 (1) , 50-56
- https://doi.org/10.1111/j.1600-0684.1993.tb00636.x
Abstract
Allelic variation at theMhcPatr‐DRand‐DQloci was studied by molecular biological techniques and compared to available HLA data. With regard to the number of allelic lineages, the chimpanzee shows a condensation of its major histocompatibility complex (MHC) class II repertoire as compared to humans. This does not have an impact on the overall degree of MHC class II polymorphism in the chimpanzee since a few lineages that are oligomorphic in humans display an extensive degree of polymorphism in the chimpanzee.Keywords
This publication has 28 references indexed in Scilit:
- Mhc-DRB and-DQA1 nucleotide sequences of three lowland gorillas: Implications for the evolution of primateMhc class II haplotypesHuman Immunology, 1993
- Evolutionary stability of transspecies major histocompatibility complex class II DRB lineages in humans and rhesus monkeysHuman Immunology, 1992
- Shared polymorphism between gorilla and human major histocompatibility complex DRB lociHuman Immunology, 1992
- Evolutionary relationships among the primate Mhc-DQA1 and DQA2 allelesImmunogenetics, 1992
- Nomenclature for factors of theHLA system, 1991Immunogenetics, 1992
- Map of the human MHCImmunology Today, 1991
- Gorilla major histocompatibility complex-DRB pseudogene orthologous to HLA-DRBVIIIHuman Immunology, 1991
- A hypothetical model of the foreign antigen binding site of Class II histocompatibility moleculesNature, 1988
- Origin of major histocompatibility complex polymorphism: The trans-species hypothesisHuman Immunology, 1987
- Leucocyte Antibodies in Sera from Pregnant WomenNature, 1958