Interferon Alfa and Zidovudine in Adult T-Cell Leukemia–Lymphoma

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Abstract
Gill et al. (June 29 issue)1 report the encouraging results of a trial in which interferon alfa and zidovudine were combined for the treatment of adult T-cell leukemia–lymphoma. The response to this treatment was impressive, and the toxicity levels were acceptable. These results may be a blessing for patients with adult T-cell leukemia–lymphoma in Japan, where more than 700 new cases are diagnosed each year among the 1.2 million carriers of the human T-cell lymphotropic virus type I.2 However, two points are not clear.