PLETHYSMOGRAPHIC DETERMINATION OF THE VOLUME OF GAS TRAPPED IN THE LUNGS 1
Open Access
- 1 June 1956
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 35 (6) , 664-670
- https://doi.org/10.1172/jci103323
Abstract
Thoracic gas volume, which includes all the compressible gas in the lungs and thorax whether in communication with the airway or not, was measured plethys-mographically at the end of normal expiration in 36 patients with cardiopulmonary or thoracic disorders. The volume of gas in the lungs in communication with the airway was measured in the same patients by the dilution or "washout" method of Darling and associates. Thoracic gas volume minus "washout" volume is the volume of "trapped" gas. In patients with pneumothorax, pulmonary cysts, emphysema and intrathoracic or pulmonary tumors (all conditions in which "trapping" of gas is known or thought to occur), the thoracic gas volume exceeded the "wash-out" volume by a significant amount (more than 0.44 1); in one patient with pulmonary cysts and emphysema the excess volume (i.e., trapped gas volume) was 3.67 1. In patients with other car-diopuln onary or thoracic disorders, no significant amount was found. The combined use of these two methods for measuring gas volumes provides a method for studying the phenomenon of gas trapping and for extending our knowledge regarding true residual volume and total lung capacity in patients with certain types of pulmonary disease.Keywords
This publication has 12 references indexed in Scilit:
- MEASUREMENT OF THE VOLUME OF GAS IN THE GASTROINTESTINAL TRACT. VALUES IN NORMAL SUBJECTS AND AMBULATORY PATIENTS 1Journal of Clinical Investigation, 1956
- A RAPID PLETHYSMOGRAPHIC METHOD FOR MEASURING THORACIC GAS VOLUME: A COMPARISON WITH A NITROGEN WASHOUT METHOD FOR MEASURING FUNCTIONAL RESIDUAL CAPACITY IN NORMAL SUBJECTS 1Journal of Clinical Investigation, 1956
- A method for the objective evaluation of bronchodilator drugsJournal of Allergy, 1955
- An Open-Circuit Helium Method for Measuring Functional Residual Capacity and Defective Intrapulmonary Gas Mixing1Journal of Clinical Investigation, 1954
- Pulmonary air cysts; some diagnostic, physiologic and therapeutic considerations.1953
- LUNG FUNCTION STUDIES. VIII. ANALYSIS OF ALVEOLAR VENTILATION BY PULMONARY N2 CLEARANCE CURVES 12Journal of Clinical Investigation, 1952
- MECHANICS OF AIRFLOW IN HEALTH AND IN EMPHYSEMAJournal of Clinical Investigation, 1951
- Lung function studiesThe American Journal of Medicine, 1951
- Pulmonary insufficiency. IV. A study of 16 cases of large pulmonary air cysts or bullae.1950
- STUDIES OF TOTAL PULMONARY CAPACITY AND ITS SUB-DIVISIONS. IV. PRELIMINARY OBSERVATIONS ON CASES OF PULMONARY EMPHYSEMA AND OF PNEUMOCONIOSISJournal of Clinical Investigation, 1933