Increased F2‐isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidationin vivo
- 1 December 1998
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 12 (15) , 1777-1783
- https://doi.org/10.1096/fasebj.12.15.1777
Abstract
Alzheimer's disease (AD) includes a group of dementing neurodegenerative disorders that have diverse etiologies but the same hallmark brain lesions. Since oxidative stress may play a role in the pa...Keywords
Funding Information
- National Institutes of Health (HL 5400, AG-09215, AG-10124, DK-44730, NSF AMX-360)
- American Federation for Aging Research (A 97122)
This publication has 48 references indexed in Scilit:
- Oxidative Stress Hypothesis in Alzheimer's DiseasePublished by Elsevier ,1998
- Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in down's syndrome and Alzheimer's DiseaseLife Sciences, 1996
- Oxidative damage in Alzheimer'sNature, 1996
- Oxidative Stress Increases Production of β-Amyloid Precursor Protein and β-Amyloid (Aβ) in Mammalian Lenses, and Aβ Has Toxic Effects on Lens Epithelial CellsPublished by Elsevier ,1996
- Generation of 8-Epiprostaglandin F by Human MonocytesJournal of Biological Chemistry, 1996
- β-Amyloid fibrils induce tau phosphorylation and loss of microtubule bindingNeuron, 1995
- Oxidative damage to mitochondrial DNA is increased in Alzheimer's diseaseAnnals of Neurology, 1994
- Hydrogen peroxide mediates amyloid β protein toxicityCell, 1994
- Amyloidogenicity of rodent and human βA4 sequencesFEBS Letters, 1993
- Autopsy Samples of Alzheimer's Cortex Show Increased Peroxidation In VitroJournal of Neurochemistry, 1990