Measurement of Functional Residual Capacity during Mechanical Ventilation by Simultaneous Exchange of Two Insoluble Gases
Open Access
- 1 May 1981
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 54 (5) , 413-417
- https://doi.org/10.1097/00000542-198105000-00012
Abstract
A precise method for rapid measurement of human functional residual capacity (FRC) during mechanical ventilation using the simultaneous exchange of Arg and N2 is described. Circuit leaks were immediately recognizable upon completion of a run and pneumotachygraphic inaccuracies due to turbulent flows, changes in viscosity and time delays between pneumotachygraph and mass spectrometer signals were avoided. For 166 duplicate determinations the 1st measurement of FRC differed from the 2nd by 0.5 .+-. 0.5% (mean .+-. SE). The technique does not affect pulmonary gas exchange. During 35 consecutive determinations of FRC (with an inspired O2 of 50%), mixed expired O2 and CO2 tensions varied less than 7 and 1.5 torr, respectively.Keywords
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