Prolyl 4-hydroxylase, a target enzyme for drug development: Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors

This publication has 15 references indexed in Scilit:

• Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor
  Biochemical Journal, 1991
• Human leukocyte C1q receptor binds other soluble proteins with collagen domains.
  The Journal of Experimental Medicine, 1990
• Beta-hydroxyaspartic acid in the first epidermal growth factor-like domain of protein C. Its role in Ca2+ binding and biological activity.
  Journal of Biological Chemistry, 1988
• The effectiveness of inhibitors of soluble prolyl hydroxylase against the enzyme in the cisternae of isolated bone microsomes
  Archives of Biochemistry and Biophysics, 1988
• Pyridinedicarboxylates, the first mechanism-derived inhibitors for prolyl 4-hydroxylase, selectively suppress cellular hydroxyprolyl biosynthesis. Decrease in interstitial collagen and Clq secretion in cell culture
  Biochemical Journal, 1987
• The Biochemical Functions of Ascorbic Acid
  Annual Review of Nutrition, 1986
• Differences between collagen hydroxylases and 2-oxoglutarate dehydrogenase in their inhibition by structural analogues of 2-oxoglutarate
  Biochemical Journal, 1985
• The 2‐oxoglutarate binding site of prolyl 4‐hydroxylase
  European Journal of Biochemistry, 1984
• A stereochemical concept for the catalytic mechanism of prolylhydroxylase
  Journal of Theoretical Biology, 1982
• Spectrophotometric Studies of the Nature of Several Iron-Pyridinecarboxylic Acid Complexes
  Bulletin of the Chemical Society of Japan, 1963