Towards microbiological quality assurance in radiation sterilization processing: the limiting case model applied to a microbial population having a distribution of radiation responses

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Abstract
A limiting case model, developed earlier to provide a conservative estimate of the proportion of non-sterile items (P) in an irradiated population of items contaminated with microorganisms of a single type, was extended to include items having organisms of different types. Estimates of P are compared with exact values derived on purely theoretical grounds and with values obtained by computer simulation of microbiological inactivation on items.