Cancer of the Gallbladder

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Abstract
We have reported a case of primary carcinoma of the gallbladder and reviewed 42 other cases seen at the Marshall University School of Medicine affiliated hospitals over the last 27 years. Most of the patients were female (74.5%) and elderly (mean age 66.9 years), and had metastatic or locally invasive disease (79%); 95% had adenocarcinoma. Preoperative diagnosis of gallbladder malignancy is rare, and long-term survival depends upon early detection. Radical surgery, chemotherapy, and radiation have not improved survival.

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