Effect of Hypoxia on Shivering

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Abstract
In a study of approximately 20 cats the animals were anesthetized with pentobarbital sodium and the anesthesia level adjusted so that shivering was absent or vigorous. The animals were than subjected to hypoxia by progressively decreasing in a 1-3-hour period the percentage of O2 in inhaled N2:O2 mixtures. Decreasing the O2 percentage between 21% and 13% had no effect on shivering. Between 13% and 8% shivering decreased until it was abolished and O2 consumption rate decreased to the nonshivering value. With nonshivering decerebrate cats, as the inhaled O2 was progressively decreased O2 consumption rate did not change until the range of 6-3% O2 was reached after which gasping respiration and apnea occurred.

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