Effect of Low-Dose Antigen Exposure on Development of Immunity to Helicobacter pylori Infection in Mice
- 1 August 2001
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 69 (8) , 5186-5188
- https://doi.org/10.1128/iai.69.8.5186-5188.2001
Abstract
The effect of low-dose antigen exposure on the development of immunity to Helicobacter pylori infection was studied in outbred mice. Animals that were primed with a subinfectious number of H. pylori bacteria exhibited significantly lower bacterial loads after challenge with an infectious dose of pathogen (versus controls, P < 0.05).Keywords
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