Nalorphine: Increased Sensitivity of Monkeys Formerly Dependent on Morphine
- 19 December 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3912) , 1548-1549
- https://doi.org/10.1126/science.166.3912.1548
Abstract
Three rhesus monkeys Macaca mulatta, formerly dependent on morphine, had increased sensitivity to nalorphine's effect of suppressing operant responding for food, as compared with two monkeys with no history of morphine exposure. Within the dose range employed, nalorphine injections produced emesis, salivation, and hyperirritability in formerly morphine-dependent monkeys but not in controls.Keywords
This publication has 3 references indexed in Scilit:
- Morphine: Single-Dose ToleranceScience, 1968
- Tolerance to and physical dependence on morphine in ratsPsychopharmacology, 1963
- CLINICAL STUDIES OF DRUG ADDICTIONArchives of internal medicine (1960), 1942