graphite - a Bioconductor package to convert pathway topology to gene network
Open Access
- 31 January 2012
- journal article
- Published by Springer Nature in BMC Bioinformatics
- Vol. 13 (1) , 20
- https://doi.org/10.1186/1471-2105-13-20
Abstract
Gene set analysis is moving towards considering pathway topology as a crucial feature. Pathway elements are complex entities such as protein complexes, gene family members and chemical compounds. The conversion of pathway topology to a gene/protein networks (where nodes are a simple element like a gene/protein) is a critical and challenging task that enables topology-based gene set analyses.Keywords
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