Allopurinol prodrugs. II. Synthesis, hydrolysis kinetics and physicochemical properties of various N-acyloxymethyl allopurinol derivatives
- 1 May 1985
- journal article
- research article
- Published by Elsevier in International Journal of Pharmaceutics
- Vol. 24 (2-3) , 307-325
- https://doi.org/10.1016/0378-5173(85)90030-4
Abstract
No abstract availableKeywords
This publication has 27 references indexed in Scilit:
- Allopurinol prodrugs. III. Water-soluble N-acyloxymethyl allopurinol derivatives for rectal or parenteral useInternational Journal of Pharmaceutics, 1985
- Prodrugs of 5-fluorouracil. IV. Hydrolysis kinetics, bioactivation and physicochemical properties of various N-acyloxymethyl derivatives of 5-fluorouracilInternational Journal of Pharmaceutics, 1985
- Allopurinol prodrugs. I. Synthesis, stability and physicochemical properties of various N1-acyl allopurinol derivativesInternational Journal of Pharmaceutics, 1985
- Hydrolysis of N-(α-hydroxybenzyl)benzamide and other N-(α-hydroxyalkyl) amide derivatives: implications for the design of N-acyloxyalkyl-type prodrugsInternational Journal of Pharmaceutics, 1984
- A simplified high-pressure liquid chromatography method for determining lipophilicity for structure-activity relationshipsJournal of Medicinal Chemistry, 1983
- Allopurinol kinetics and bioavailabilityCancer Chemotherapy and Pharmacology, 1982
- N-Hydroxymethyl Derivatives of Nitrogen Heterocycles as Possible Prodrugs II: Possible Prodrugs of Allopurinol, Glutethimide, and PhenobarbitalJournal of Pharmaceutical Sciences, 1981
- Pro-drugs as drug delivery systems VIII. Bioreversible derivatization of hydantoins by N-hydroxymethylationInternational Journal of Pharmaceutics, 1980
- Studies on the chemical reactivity and the physical properties of allopurinol (pyrazolo[3,4-d]pyrimidin-4-one) and related compoundsJournal of the Chemical Society, Perkin Transactions 1, 1979
- Allopurinol and Other Inhibitors of Urate SynthesisPublished by Springer Nature ,1978