1,3-Dipolar Cycloaddition of Nitrile Functions with Nitrones under High Pressure Conditions. A New and Direct Synthesis of 2,3-Dihydro-1,2,4-Oxadiazole Derivatives
- 1 May 1995
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1995 (05) , 498-500
- https://doi.org/10.1055/s-1995-3949
Abstract
Usual nitrile functions underwent 1,3-dipolar cycloaddition reactions with 4-azahomoadamant-4-ene N-oxides 1 and 2, 5,5-dimethylpyrroline N-oxide (3), and benzylidenephenylamine N-oxide (4) smoothly under high pressure conditions to provide a new and direct method for synthesis of 2,3-dihydro-1,2,4-oxadiazole (Δ 4-1,2,4-oxadiazoline) derivatives.Keywords
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