Vaccination strategies for an influenza pandemic.
Open Access
- 15 April 2005
- journal article
- editorial
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 191 (8) , 1207-1209
- https://doi.org/10.1086/428952
Abstract
An influenza pandemic represents one of the greatest acute infectious threats to health. The 1918–1919 influenza pandemic caused an estimated 500,000 deaths in the United States, making it the most fatal event in all of US history. The spread of highly pathogenic avian H5N1 influenza across much of Asia creates a substantial risk of igniting the next pandemic. In 2004, 44 human cases caused by this strain were documented and resulted in 32 deaths. The evolution of a strain that is effectively transmitted between people may be a single reassortment event away or could occur through continuing mutationKeywords
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