Novel 3- N -Aminoglycoside Acetyltransferase Gene, aac ( 3 )- Ic , from a Pseudomonas aeruginosa Integron
Open Access
- 1 May 2003
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (5) , 1746-1748
- https://doi.org/10.1128/aac.47.5.1746-1748.2003
Abstract
A novel gene, aac ( 3 )- Ic , encoding an AAC(3)-I aminoglycoside 3- N -acetyltransferase, was identified on a gene cassette inserted into a Pseudomonas aeruginosa integron that also carries a bla VIM-2 and a cmlA7 gene cassette. The aac ( 3 )- Ic gene product is 59 and 57% identical to AAC(3)-Ia and AAC(3)-Ib, respectively, and confers resistance to gentamicin and sisomicin.Keywords
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