Normal Mucoprotein Values in the Dog; Response to Distemper Vaccine and to Endocarditis

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Abstract
The normal serum mucoprotein-tyrosine level in 55 dogs was found to be 2.5 mg. % [plus or minus] 0.11, which value corresponds closely to that for normal humans. Distemper vaccine produced a temporary, but significant elevation in the mucoprotein-tyrosine level in dogs. The peak response of serum mucoprotein-tyrosine levels to the distemper vaccine was reached in 2 weeks, and returned to normal in the majority of animals by 7 weeks. A statistically significant elevation of mucoprotein-tyrosine levels occurred in response to the physiol. stress of large arteriovenous fistula loads. A much greater elevation was found in dogs with large arteriovenous fistulas and endocarditis produced by beta hemolytic streptococci.