Comparative activities of the beta-lactamase inhibitors YTR 830, sodium clavulanate, and sulbactam combined with amoxicillin or ampicillin
Open Access
- 1 October 1984
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 26 (4) , 580-582
- https://doi.org/10.1128/aac.26.4.580
Abstract
YTR 830, a new beta-lactamase inhibitor, was compared with clavulanic acid and sulbactam against aminopenicillin-resistant clinical isolates. At a concentration of 8 micrograms/ml, YTR 830 was as effective as clavulanate or sulbactam in reducing the aminopenicillin MICs. Combined with amoxicillin, YTR 830 is a potentially useful agent for therapy of many bacterial infections.Keywords
This publication has 2 references indexed in Scilit:
- Plasmid-determined β-lactamases identified in a group of 204 ampicillin-resistant EnterobacteriaceaeJournal of Antimicrobial Chemotherapy, 1983
- The β-lactamases of Gram-negative bacteria and their rôle in resistance to β-lactam antibioticsJournal of Antimicrobial Chemotherapy, 1976