Evaluation of Antimycobacterial, Antiplasmodial and Cytotoxic Activities of Preussomerins Isolated from the Lichenicolous Fungus Microsphaeropsis sp. BCC 3050
- 31 January 2002
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 68 (1) , 45-48
- https://doi.org/10.1055/s-2002-20055
Abstract
A new preussomerin isomer, 3′-O-demethylpreussomerin I, five known preussomerins E - I, and two known deoxypreussomerins, deoxypreussomerin A and bipendensin (palmarumycin C11), were isolated from a lichenicolous fungus Microsphaeropsis sp. BCC 3050. These structures were elucidated by spectroscopic methods, especially 1D- and 2D-NMR. The preussomerins were evaluated for their antimycobacterial and antiplasmodial activities as well as cytotoxicity against KB, BC-1 and vero cell lines.Keywords
This publication has 0 references indexed in Scilit: