Time and Theophylline Concentration Help Explain the Recovery of Peak Flow Following Acute Airways Obstruction
- 1 December 1993
- journal article
- clinical trial
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 25 (6) , 506-515
- https://doi.org/10.2165/00003088-199325060-00008
Abstract
Peak expiratory flow rate, adverse effects and serum theophylline concentration were measured during treatment of episodes of severe airways obstruction. 174 patients were randomised to target...Keywords
This publication has 9 references indexed in Scilit:
- Theophylline Target Concentration in Severe Airways Obstruction - 10 or 20 mg/L?Clinical Pharmacokinetics, 1993
- Nonlinear Mixed Effects Models for Repeated Measures DataPublished by JSTOR ,1990
- Pulmonary Function in the Elderly: Response to Theophylline BronchodilationThe Journal of Clinical Pharmacology, 1990
- A Randomized, Controlled Trial of Theophylline in Patients with Severe Chronic Obstructive Pulmonary DiseaseNew England Journal of Medicine, 1989
- AMINOPHYLLINE INCREASES THE TOXICITY BUT NOT THE EFFICACY OF AN INHALED BETA-ADRENERGIC AGONIST IN THE TREATMENT OF ACUTE EXACERBATIONS OF ASTHMAPublished by Elsevier ,1985
- PREDNISOLONE PHARMACODYNAMICS ASSESSED BY INHIBITION OF THE MIXED LYMPHOCYTE REACTIONTransplantation, 1982
- THEOPHYLLINE SERUM CONCENTRATION AND THERAPEUTIC EFFECT IN SEVERE ACUTE BRONCHIAL OBSTRUCTION - THE OPTIMAL USE OF INTRAVENOUSLY ADMINISTERED AMINOPHYLLINEPublished by Elsevier ,1982
- Understanding the Dose-Effect RelationshipClinical Pharmacokinetics, 1981
- Rational Intravenous Doses of TheophyllineNew England Journal of Medicine, 1973