Evidence for a Genetic Duplication involving Alcohol Dehydrogenase Genes in Drosophila huzzatii and Related Species
Open Access
- 1 January 1982
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Biological Sciences
- Vol. 35 (1) , 73-84
- https://doi.org/10.1071/bi9820073
Abstract
Drosophila buzzatii has two closely linked loci (0· 4 ± O· 3 cM apart) encoding NAD + -dependent alcohol dehydrogenase. These two loci produce complex, non-overlapping electrophoretic phenotypes and differ in their ontogenetic expression, that of Adh-l relative to Adh-2 being less in adults than in third-instar larvae. Isozymes produced by the two Adh-2 alleles analysed have similar in vitro ADH activity levels, substrate specificities and thermostabilities, whereas the isozymes of the two Adh-l alleles examined differ in ADH activity and specificity for primary versus secondary alcohol substrates.Keywords
This publication has 1 reference indexed in Scilit:
- Extension of longevity in Drosophila mojavensis by environmental ethanol: differences between subraces.Proceedings of the National Academy of Sciences, 1977