VARIATION IN OSMOREGULATION OF ARGININE VASOPRESSIN DURING THE HUMAN MENSTRUAL CYCLE
- 1 January 1985
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 22 (1) , 37-42
- https://doi.org/10.1111/j.1365-2265.1985.tb01062.x
Abstract
SUMMARY: Osmoregulation of vasopressin secretion was studied in eight healthy women in the follicular and luteal phases of the menstrual cycle. Basal plasma osmolality in the luteal phase was significantly lower than in the follicular period (282·4±0·6, 285·6 ± 1·1 mmol/kg, respectively, Pr=+0·93, (ii) luteal, pAVP = 0·31 (pOsm‐279), r=+0·95. Both the slope and abscissal intercept were significantly different (PP<0·005). We conclude that, in the luteal phase, the threshold for AVP release and the gain or sensitivity of the osmostat are reduced together with lowering of the thirst threshold, which account for the lower basal luteal plasma osmolality.This publication has 20 references indexed in Scilit:
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