LOCALIZATION OF BLOOD-GROUP-A AND I-ANTIGENIC SITES ON INSIDE-OUT AND RIGHTSIDE-OUT HUMAN ERYTHROCYTE-MEMBRANE VESICLES

  • 1 January 1979
    • journal article
    • research article
    • Vol. 36  (1) , 33-36
Abstract
Investigations on the fixation of 125I-labeled anti-A and anti-I antibodies [Ab] onto rightside-out and inside-out membrane vesicles prepared from human A1 and OI erythrocytes, respectively, showed that both Ab were bound to the rightside-out vesicles, giving clear evidence that blood group A and I antigenic sites are exclusively localized on the external surface of the membrane.