Thrombocytosis and thrombocytopenia in childhood bacterial meningitis

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Abstract
To assess factors affecting the development of reactive thrombocytosis during bacterial meningitis, thrombocyte counts of 311 children with cerebrospinal fluid culture-positive bacterial meningitis were followed during hospitalization. Thrombocytosis (platelet counts >500x109/liter) was seen in 49% of the patients after the first week of tratment. Thrombocyte counts were higher in infants and in patients with long duration of illness before admission. Subdural effusion and cephalosporin therapy were associated with more pronounced thrombocytosis. We found no relation between thrombocytosis

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