The effect of faecal loading on colonic anastomotic healing
- 1 January 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 70 (1) , 49-50
- https://doi.org/10.1002/bjs.1800700119
Abstract
The effect of faecal loading of the colon on the healing of rat colonic anastomoses has been investigated in a prospective randomized and controlled study. Anastomotic dehiscence occurred significantly more often when the bowel was loaded with faeces at the time of operation than when it was empty. Suture line cultures bore no relationship to the outcome of the anastomosis. This result emphasizes the importance of an empty colon as a contributory factor in successful colonic healing in the rat.Keywords
This publication has 13 references indexed in Scilit:
- Antibiotic-Associated Pseudomembranous Colitis Due to Toxin-Producing ClostridiaNew England Journal of Medicine, 1978
- WHOLE-GUT IRRIGATION IN PREPARATION FOR LARGE-BOWEL SURGERYThe Lancet, 1973
- Aetiology of disruption of intestinal anastomosesBritish Journal of Surgery, 1973
- Factors Contributing to Leakage of Colonic AnastomosesAnnals of Surgery, 1973
- Preparation of the intestine in patients undergoing major large-bowel surgery, mainly for neoplasms of the colon and rectumBritish Journal of Surgery, 1971
- The relative significance of preoperative oral antibiotics, mechanical bowel preparation, and preoperative peritoneal contamination in the avoidance of sepsis after radical surgery for ulcerative colitis and Crohn's disease of the large bowelBritish Journal of Surgery, 1971
- The effect of surrounding infection upon the healing of colonic woundsDiseases of the Colon & Rectum, 1970
- The place of antibiotics in colonic surgery: A clinical studyBritish Journal of Surgery, 1969
- Staphylococcal Enterocolitis Following Antibiotic TherapyAnnals of Surgery, 1963
- Antibiotic Protection of Colon Anastomoses*Annals of Surgery, 1955