Expression of the Activated p185erbB2Tyrosine Kinase in Human Epithelial Cells Leads to MAP Kinase Activation but Does Not Confer Oncogenicity
- 15 March 1997
- journal article
- Published by Elsevier in Experimental Cell Research
- Vol. 231 (2) , 251-259
- https://doi.org/10.1006/excr.1996.3468
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- SH2/SH3 signaling proteinsPublished by Elsevier ,2004
- p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases.Proceedings of the National Academy of Sciences, 1992
- Expression of the p185 encoded by her2 oncogene in normal and transformed human tissuesInternational Journal of Cancer, 1990
- erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 CellsScience, 1987
- Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.Molecular and Cellular Biology, 1987
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987
- Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185Cell, 1986
- A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.Proceedings of the National Academy of Sciences, 1985
- Amplification of a Novel v- erb B-Related Gene in a Human Mammary CarcinomaScience, 1985
- The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigenNature, 1984