A convenient synthesis of 1-(S)-[1′-(S)-(t-butyloxycarbonylamino)-2′-phenylethyl]oxirane. A useful building block in the synthesis of HIV protease inhibitors

This publication has 24 references indexed in Scilit:

• Progress in the discovery of orally bioavailable inhibitors of HIV protease
  Perspectives in Drug Discovery and Design, 1995
• The synthesis of novel HIV-protease inhibitors
  Bioorganic & Medicinal Chemistry, 1994
• Stereoselective synthesis of protected amino alkyl epoxides
  Tetrahedron Letters, 1994
• Studies toward the Large-Scale Synthesis of the HIV Proteinase Inhibitor Ro 31-8959
  The Journal of Organic Chemistry, 1994
• New dipeptide isosteres useful for the inhibition of HIV-1 protease
  Bioorganic & Medicinal Chemistry Letters, 1994
• Novel HIV01 protease inhibitors containing A β-hydroxy sulfide isostere.
  Bioorganic & Medicinal Chemistry Letters, 1994
• Inhibitors of HIV proteinase
  Expert Opinion on Investigational Drugs, 1994
• A facile and enantiospecific synthesis of 2(S)- and 2 (R)[1′(S)-azido-2-phenylethyl]oxirane
  Journal of the Chemical Society, Chemical Communications, 1992
• Rational Design of Peptide-Based HIV Proteinase Inhibitors
  Science, 1990
• A stereocontrolled synthesis of hydroxyethylene dipeptide isosteres using novel, chiral aminoalkyl epoxides and .gamma.-(aminoalkyl)-.gamma.-lactones
  The Journal of Organic Chemistry, 1985